Shanghai Allist Pharmaceuticals Co., Ltd. is a biotech with integrated capabilities in the R&D, manufacturing and commercialization of small-molecule medicine. Our mission is to improve the life quality and health of all human beings. Driven by innovation of R&D, Allist strives to develop the first-in-class and best-in-class drugs.Since the establishment of Allist in 2004, it has built a strong in-house drug R&D platform and successfully developed 2 new drugs in the past 16 years.
Allist has built a strong product pipeline focusing on the NSCLC. Furmonertinib, its core product, is a 3G EGFR-TKI with strong performance in safety and efficacy both for primary lung cancer and brain metastasis. With the GMP compliant manufacturing facilities, Furmonertinib, has been commercialized in Mar 2021 for the indication of second-line treatment of EGFR+ NSCLC, and more indications of Furmonertinib are under development. The undergoing Ib clinical trial of Furmonertinib has shown great potential for the treatment of NSCLC patients with EGFR Ex20ins mutation. The KRAS-G12C inhibitor and RET inhibitor under development are expected to enter the clinical trial in 2022. Other pre-clinical products under development include KRAS G12D inhibitor, 4th-generation EGFR-TKI and SOS1 inhibitor.
The management team of Allist boasts a wealth of experience on EGFR-TKIs and PD-1/PD-L1 immune-checkpoint inhibitors. For the commercialization of Furmonertinib, Allist has also built a professional medical, marketing and sales function team whose members have an industry-envy and highly focused oncology expertise, especially in the NSCLC area in China.
|Earnings Per Share||-0.84||-1.10||-|
|R&D expenditure as a % of operating revenue||31728.84%||25,725.39%||2,001.90%|
|Total Owners' Equity||2,878.05||1,184.39||71.03|
|Net Cash Flows-Operating||-196.75||-259.37||-97.25|
|Net Cash Flows-Investing||-1,742.78||-622.42||39.17|
|Net Cash Flows-Financing||1,913.14||1,152.47||122.15|
|Name||No. of Shares Held (mn)||% of Shares Held|
|JEFFREY YANG GUO||25.62||5.69%|
|JIN HAO DU||10.80||2.40%|
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