Brief Introduction

Founded in December 2012, Junshi Biosciences (HK: 1877; SH: 688180) is an innovation-driven biopharmaceutical company dedicated to the discovery, development and commercialization of innovative therapeutics. On December 24, 2018, Junshi Biosciences was listed on the Main Board of the Stock Exchange of Hong Kong with the stock code: 1877.HK. On July 15, 2020, the Company was listed on the STAR Market of the Shanghai Stock Exchange with the stock code: 688180.SH.

Junshi Biosciences has established a diversified R&D pipeline comprising 26 innovative drug candidates and 2 biosimilars, with five therapeutic focus areas covering cancer, autoimmune, metabolic, neurologic, and infectious diseases. The Company was the first Chinese pharmaceutical company that obtained marketing approval for PD-1 monoclonal antibody in China and clinical trial application approval for anti PCSK9 monoclonal antibody from NMPA. The world's first in human anti-BTLA antibody for solid tumors was officially approved for clinical trials by the FDA and NMPA. From this year onwards, Junshi Biosciences pooled its efforts with Chinese science institutions to co-develop JS016, China's first neutralizing human monoclonal antibodies against SARS-CoV-2, that has entered clinical trial, part of our continuous innovation for disease control and prevention in China and beyond.

Junshi Biosciences has independently developed and established an integrated technology system covering the entire lifecycle of protein drugs from early R&D to industrialization. The system involves seven technology platforms, which are (i)automated high-efficiency screening platform for antibody selection and functional assays, (ii)high-yielding stable expression cell lines screening and establishment platform, (iii)antibody humanization and construction platform, (iv)CHO cell fermentation process development platform, (v)antibody purification process development and formulation optimization platform, (vi)human transmembrane receptor protein array and high-throughput screening platform and (vii)antibody quality research, control and assurance platform. Meanwhile, a globally integrated R&D process has been established. With four R&D centers worldwide, the Company has outstanding ability to discover and develop innovative biologics drugs, including key steps, i.e. independent target assessment, mechanism study and validation, clinical drug screening and functional validation, etc. In regard to production, the Company has two monoclonal antibody production bases with combined 33,000L fermentation capacity in China, located in Suzhou Wujiang and Shanghai Lingang. The two established manufacturing infrastructures can support commercialization and provide our partners and patients with high quality products through a global supply chain network.

With strong R & D capacity, Junshi Biosciences is at the cutting-edge of medical innovation, taking "Providing patients with world-class, trustworthy, and affordable innovative drugs" as its mission.

Company Overview

Full name Shanghai Junshi Biosciences Co., Ltd
Abbreviations Junshi Biosciences
Code 688180
Founded 27/12/2012
Listing 15/07/2020
Domicile Shanghai
STAR Theme Biomedicine
CSRCSector Manufacturing
Has weighted voting rights structure? No



  2019 2018 2017
Earnings Per Share -0.96 -1.21 -0.55
R&D expenditure as a % of operating revenue 122.06% 18,383.07% 505.15%
Operating Revenue 775.09 2.93 54.50
Net Income -747.73 -722.85 -317.57

Income Statement (Unit: RMB mn)

  2019 2018 2017
Operating Revenue 775.09 2.93 54.50
Operating Costs 1,567.88 709.64 353.41
Operating Income -738.89 -719.30 -317.53
Pretax Income -766.62 -724.07 -317.51
Income Tax -18.89 -1.21 0.06
Net Income -747.73 -722.85 -317.57

Balance Sheet(Unit: RMB mn)

  2019 2018 2017
Current Assets-Total 1,911.12 2,910.18 515.33
Non-current Assets-Total 2,500.84 1,340.14 704.38
Total Assets 4,411.95 4,250.32 1,219.71
Current Liabilities-Total 578.23 471.07 58.56
Non-current Liabilities-Total 855.70 465.11 41.81
Total Liabilities 1,433.92 936.18 100.37
Stockholder's Equity
Share Capital 4,964.57 4,557.55 1,641.16
Retained Profits -1,986.53 -1,242.29 -520.65
Minority interests 0.00 -1.11 -1.17
Total Owners' Equity 2,978.03 3,314.14 1,119.33

Cash Flow Statement (Unit: RMB mn)

  2019 2018 2017
Net Cash Flows-Operating -1,179.48 -516.95 -311.30
Net Cash Flows-Investing -959.59 -414.79 151.94
Net Cash Flows-Financing 593.58 3,432.60 319.63

Top 10 Shareholders

Name No. of Shares Held (mn) % of Shares Held
Xiong Jun(熊俊) 87.25 10.01%
Shanghai Tanying Investment Partnership (LP)(上海檀英投资合伙企业(有限合伙)) 76.59 8.79%
Suzhou Ruiyuan Shengben Biological Medicine Management Partnership (LP)(苏州瑞源盛本生物医药管理合伙企业(有限合伙)) 43.58 5.00%
Xiong Fengxiang(熊凤祥) 41.06 4.71%
珠海高瓴天成股权投资基金(有限合伙) 25.20 2.89%
Huang Fei(黄菲) 22.59 2.59%
Zhou Yuqing(周玉清) 21.68 2.49%
Qiao Xiaohui(乔晓辉) 16.50 1.89%
Wang Shujun(王树君) 15.81 1.82%
30 Sep 2020

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